Term Name: | reelin complex |
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Synonyms: | |
Definition: | An extracellular complex that binds lipoprotein receptors VLDLR and APOER2, cadherin-related neuronal receptors (CNRs) or alpha3beta1 integrin and induces various downstream, reelin-dependent, phosphorylation cascades. It ultimately affects polarization, differentiation, neuronal migration and layer formation in the embryonic brain and neuron growth, maturation, and synaptic activity in the postnatal and adult brain. |
Ontology: | GO: Cellular Component [GO:0110157] QuickGO AmiGO |