Term Name: | ubiquitin-dependent glycoprotein ERAD pathway |
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Synonyms: | ER-associated glycoprotein degradation, glycoprotein ERAD, gpERAD, misfolded or incompletely synthesized glycoprotein catabolic process |
Definition: | An ERAD pathway whereby endoplasmic reticulum (ER)-resident glycoproteins are targeted for degradation. Includes differential processing of the glycoprotein sugar chains, retrotranslocation to the cytosol and degradation by the ubiquitin-proteasome pathway. A glycoprotein is a compound in which a carbohydrate component is covalently bound to a protein component. |
Ontology: | GO: Biological Process [GO:0097466] QuickGO AmiGO |