Term Name: apoptotic signaling pathway
Synonyms: apoptotic signalling pathway, induction of apoptosis by extracellular signals
Definition: The series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered.
Ontology: GO: Biological Process [GO:0097190]    QuickGO    AmiGO

Relationships
is part of: apoptotic process
has parts: apoptosome assembly mitochondrial outer membrane permeabilization release of cytochrome c from mitochondria
is a type of: signal transduction
has subtype: extrinsic apoptotic signaling pathway granzyme-mediated apoptotic signaling pathway hormone-mediated apoptotic signaling pathway intrinsic apoptotic signaling pathway
inverse has_part: apoptotic process
negatively regulated by: negative regulation of apoptotic signaling pathway
positively regulated by: positive regulation of apoptotic signaling pathway
regulated by: regulation of apoptotic signaling pathway