Term Name: | transforming growth factor beta activated kinase 1 complex |
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Synonyms: | TAK1 kinase complex |
Definition: | A protein complex that possesses protein kinase activity and activates the I-kappa B kinase complex (IKK) and mitogen-activated protein (MAP) kinases in response to TRAF6 signaling. It comprises the catalytic subunit TAK1 complexed to the regulatory subunits, termed TABs (TAK1-binding subunits). |
Ontology: | GO: Cellular Component [GO:0097076] QuickGO AmiGO |