Term Name: | SMAD protein complex |
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Synonyms: | SMAD complex, SMAD1 protein complex, SMAD2 protein complex, SMAD3 protein complex |
Definition: | A protein complex that consists of only SMAD proteins; may be homomeric or heteromeric. Heteromeric complexes act as transcription factors while homomeric complexes exist but are transcriptionally inactive. Hetero- versus homotrimerization is largely enthalpy driven. |
Ontology: | GO: Cellular Component [GO:0071141] QuickGO AmiGO |