Term Name: | TIR domain binding |
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Synonyms: | Toll-Interleukin receptor domain binding |
Definition: | Binding to a Toll-Interleukin receptor (TIR) domain of a protein. The TIR domain is an intracellular 200 residue domain that is found in the Toll protein, the interleukin-1 receptor (IL-1R), and MyD88; it contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. |
Ontology: | GO: Molecular Function [GO:0070976] QuickGO AmiGO |