Term Name: | BRCA1-C complex |
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Synonyms: | |
Definition: | A protein complex that contains the BRCA1-BARD1 heterodimer, CtIP and Mre11/Rad50/NBS1 (M/R/N) complex, and binds to DNA at DNA damage sites. BRCA1-C binding ta damaged DNA is required for DNA damage-induced Chk1 phosphorylation and the G2/M transition checkpoint. |
Ontology: | GO: Cellular Component [GO:0070533] QuickGO AmiGO |