Term Name: | death domain binding |
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Synonyms: | |
Definition: | Binding to a death domain of a protein. The death domain (DD) is a homotypic protein interaction module composed of a bundle of six alpha-helices. DD bind each other forming oligomers. Some DD-containing proteins are involved in the regulation of apoptosis and inflammation through their activation of caspases and NF-kappaB. |
Ontology: | GO: Molecular Function [GO:0070513] QuickGO AmiGO |