Term Name: | acyl-CoA delta5-desaturase activity |
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Synonyms: | acyl-CoA (8-3)-desaturase, acyl-CoA D5-desaturase activity, acyl-CoA delta(5)-desaturase activity |
Definition: | Catalysis of the reaction: (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O. Can also use a substrate with 3 double bonds (a (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA) and add a fourth double bond (a (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA). |
Ontology: | GO: Molecular Function [GO:0062076] QuickGO AmiGO |