Term Name: | telomeric DNA-containing double minutes formation |
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Synonyms: | TDMs formation |
Definition: | A telomere maintenance process that results in the formation of small fragments of circular extrachromosomal DNA elements which contain telomeric DNA. It is speculated that telomeric DNA-containing double minutes are formed through a recombination event between the telomere and chromosome-internal TTAGGG-like sequences. Telomeric DNA-containing double minutes appear as two closely positioned dots in metaphase. |
Ontology: | GO: Biological Process [GO:0061819] QuickGO AmiGO |