Term Name: | type 2 mitophagy |
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Synonyms: | Park2-mediated mitophagy in response to mitochondrial depolarization, parkin-mediated mitophagy in response to mitochondrial depolarization, PRKN-mediated mitophagy in response to mitochondrial depolarization |
Definition: | The selective autophagy process in which a mitochondrion is degraded by macroautophagy in a process initiated by mitochondrial depolarization (mtDepo) followed by Parkin binding, and ubiquitination of outer membrane proteins, to remove potentially harm-inducing dysfunctional/damaged mitochondria. |
Ontology: | GO: Biological Process [GO:0061734] QuickGO AmiGO |