Term Name: | NEDD8 ligase activity |
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Synonyms: | |
Definition: | Catalysis of the transfer of NEDD8 to a substrate protein via the reaction X-NEDD8 + S = X + S-NEDD8, where X is either an E2 or E3 enzyme, the X-NEDD8 linkage is a thioester bond, and the S-NEDD8 linkage is an isopeptide bond between the C-terminal amino acid of NEDD8 and the epsilon-amino group of lysine residues in the substrate. |
Ontology: | GO: Molecular Function [GO:0061663] QuickGO AmiGO |