Term Name:	large conductance calcium-activated potassium channel activity
Synonyms:	BK calcium-activated potassium channel activity, BK channel activity, BK KCa channel activity, large conductance KCa channel activity
Definition:	Enables the transmembrane transfer of potassium by a channel with a unit conductance of 100 to 220 picoSiemens that opens in response to stimulus by concerted actions of internal calcium ions and membrane potential. Large conductance calcium-activated potassium channels are less sensitive to calcium than are small or intermediate conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism.
Ontology:	GO: Molecular Function [GO:0060072]    QuickGO    AmiGO