Term Name: | class II DNA-(apurinic or apyrimidinic site) endonuclease activity |
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Synonyms: | abasic deoxyendoribonuclease activity, AP deoxyendoribonuclease activity, apurinic deoxyendoribonuclease activity, apyrimidinic deoxyendoribonuclease activity, class II AP endonuclease activity, class II DNA-(apurinic or apyrimidinic site) lyase activity |
Definition: | Catalysis of the hydrolysis of ester linkages immediately 5' to an apurinic/apyrimidinic (AP; also called abasic) site within a deoxyribonucleic acid molecule by creating internal breaks, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. |
Ontology: | GO: Molecular Function [GO:0052720] QuickGO AmiGO |