Term Name:	lysine biosynthetic process via alpha-aminoadipate and saccharopine
Synonyms:	lysine biosynthesis via aminoadipic acid and saccharopine, lysine biosynthetic process via aminoadipic acid and saccharopine
Definition:	The chemical reactions and pathways resulting in the formation of lysine via the intermediates alpha-aminoadipic acid and saccharopine. This pathway is used by yeast and fungi to synthesize the essential amino acid L-lysine, and pathway intermediates are often incorporated into secondary metabolic processes. The pathway proceeds as follows: alpha-ketoglutarate is converted to homocitrate, which is metabolized to 3-carboxyhex-2-enedioate and then homoisocitrate. This is then decarboxylated to form alpha-ketoadipate, which is then converted to alpha-aminoadipate. This is then reduced to form alpha-aminoadipate 6-semialdehyde, which is metabolized to saccharopine and finally L-lysine.
Ontology:	GO: Biological Process [GO:0051975]    QuickGO    AmiGO