Term Name: | isotype switching to IgA isotypes |
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Synonyms: | class switching to IgA isotypes, isotype switch recombination to IgA isotypes |
Definition: | The switching of activated B cells from IgM biosynthesis to biosynthesis of an IgA isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and one of the IgA constant region gene segments in the immunoglobulin heavy chain locus. |
Ontology: | GO: Biological Process [GO:0048290] QuickGO AmiGO |