Term Name:	1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity
Synonyms:	phosphatidylinositol 3-kinase activity, class I, phosphatidylinositol 3-kinase activity, class II, phosphatidylinositol 3-kinase, class I, catalyst activity, phosphatidylinositol-4,5-bisphosphate 3-kinase activity, type I phosphoinositide 3-kinase activity
Definition:	Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + ADP + H+.
Ontology:	GO: Molecular Function [GO:0046934]    QuickGO    AmiGO