Term Name:	pyruvate dehydrogenase complex
Synonyms:	dihydrolipoyl dehydrogenase complex, pyruvate dehydrogenase complex (lipoamide)
Definition:	A multi-enzyme complex that catalyzes the oxidative decarboxylation of pyruvate to form acetyl-CoA. The complex comprises multiple copies of three enzymes referred to as E1, E2 and E3: pyruvate dehydrogenase (E1, which may be a homodimer or a heterotetramer of two alpha and two beta subunits, depending on species), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). Additional proteins may also be present.
Ontology:	GO: Cellular Component [GO:0045254]    QuickGO    AmiGO