Term Name: protein targeting to ER
Synonyms: protein targeting to endoplasmic reticulum, protein-endoplasmic reticulum targeting, protein-ER targeting
Definition: The process of directing proteins towards the endoplasmic reticulum (ER) using signals contained within the protein. One common mechanism uses a 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, which directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane.
Ontology: GO: Biological Process [GO:0045047]    QuickGO    AmiGO

Relationships
is a type of: establishment of protein localization to endoplasmic reticulum protein targeting
has subtype: post-translational protein targeting to endoplasmic reticulum membrane SRP-dependent cotranslational protein targeting to membrane