Term Name:	phosphatidylinositol 3-kinase/protein kinase B signal transduction
Synonyms:	AKT signal transduction, AKT signaling, AKT signaling cascade, AKT signalling cascade, phosphatidylinositol 3-kinase signaling/protein kinase B signal transduction, PI3K-PKB/Akt pathway, PI3K/Akt signal transduction, PI3K/PKB signal transduction, PKB signal transduction, PKB signaling, PKB signaling cascade, PKB signalling cascade, protein kinase B signal transduction, protein kinase B signaling, protein kinase B signaling cascade, protein kinase B signalling cascade
Definition:	An intracellular signaling cassette that starts with phosphatidylinositol 3-kinase (PI3K) activation, production of phosphatidylinositol 3-phosphate (PI3P), activation of PDK1, which recruits and ending with the activation of protein kinase B (PKB, also known as Akt). PI3K is activated by cell surface receptors. Note that PTEN is an inhibitor of the pathway.
Ontology:	GO: Biological Process [GO:0043491]    QuickGO    AmiGO