Term Name: | Fanconi anaemia nuclear complex |
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Synonyms: | FA complex, FA core complex, FA nuclear complex, Fanconi anaemia complex |
Definition: | A protein complex composed of the Fanconi anaemia (FA) proteins including A, C, E, G and F (FANCA-F). Functions in the activation of the downstream protein FANCD2 by monoubiquitylation, and is essential for protection against chromosome breakage. |
Ontology: | GO: Cellular Component [GO:0043240] QuickGO AmiGO |