Term Name: | ATP-binding cassette (ABC) transporter complex |
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Synonyms: | ABC-type efflux permease complex, ABC-type efflux porter complex, ABC-type uptake permease complex, mating pheromone exporter |
Definition: | A complex for the transport of metabolites into and out of the cell, typically comprised of four domains; two membrane-associated domains and two ATP-binding domains at the intracellular face of the membrane, that form a central pore through the plasma membrane. Each of the four core domains may be encoded as a separate polypeptide or the domains can be fused in any one of a number of ways into multidomain polypeptides. In Bacteria and Archaebacteria, ABC transporters also include substrate binding proteins to bind substrate external to the cytoplasm and deliver it to the transporter. |
Ontology: | GO: Cellular Component [GO:0043190] QuickGO AmiGO |