Term Name: | TIM22 mitochondrial import inner membrane insertion complex |
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Synonyms: | mitochondrial inner membrane protein insertion complex, mitochondrial protein translocase complex, Tim22 complex |
Definition: | A multi-subunit complex embedded in the mitochondrial inner membrane that mediates the inner membrane insertion of multi-transmembrane spanning proteins that contain internal targeting elements. In yeast cells, TIM22 is a 300-kDa complex, consisting of four membrane integral subunits, Tim22, Tim54, Tim18 and Sdh3, and a peripheral chaperone complex consisting of the small TIM proteins, Tim9-Tim10-Tim12. |
Ontology: | GO: Cellular Component [GO:0042721] QuickGO AmiGO |