Term Name: | ATPase-coupled transmembrane transporter activity |
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Synonyms: | ABC transporter, ABC-type efflux permease activity, ABC-type efflux porter activity, ABC-type uptake permease activity, ATP binding cassette transporter, ATP-binding cassette (ABC) transporter activity, ATP-binding cassette transporter, ATP-coupled transmembrane transporter activity, ATP-dependent transmembrane transporter activity, ATPase activity, coupled to movement of substances, ATPase activity, coupled to transmembrane movement of substances, hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances, mating pheromone exporter, P-P-bond-hydrolysis-driven transmembrane transporter activity, P-P-bond-hydrolysis-driven transporter |
Definition: | Primary active transporter of a solute across a membrane, via the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of a substance across a membrane. The transport protein may be transiently phosphorylated (P-type transporters), or not (ABC-type transporters and other families of transporters). Primary active transport occurs up the solute's concentration gradient and is driven by a primary energy source. |
Ontology: | GO: Molecular Function [GO:0042626] QuickGO AmiGO |