Term Name: | symbiont-mediated suppression of host JAK-STAT cascade via inhibition of host TYK2 activity |
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Synonyms: | disruption by virus of host JAK-STAT cascade via inhibition of host TYK2 activity, suppression by virus of host JAK-STAT cascade via inhibition of host TYK2 activity, suppression by virus of host non-receptor tyrosine-protein kinase TYK2 activity, suppression by virus of host TYK2 activity |
Definition: | A process in which a symbiont interferes with, inhibits or disrupt a JAK-STAT signal cascade in the host organism by reducing the activity of host TYK2 (tyrosine kinase 2). TYK2 is an intracellular signal-transducing tyrosine kinase involved in numerous cytokines and interferons signaling pathways and transmits the cytokine signal by phosphorylating receptor subunits. |
Ontology: | GO: Biological Process [GO:0039574] QuickGO AmiGO |