Term Name:	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
Synonyms:	inhibition by virus of host MDA-5 signaling, inhibition of host IFIH1/MDA5 by virus, Inhibition of host MDA5 by virus, suppression by virus of host IFIH1 signaling pathway, suppression by virus of host MDA-5 activity, suppression by virus of host MDA-5 signaling pathway, suppression by virus of host MDA-5 signalling pathway, suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity
Definition:	A process in which a symbiont interferes with, inhibits or disrupts a cytoplasmic pattern recognition receptor signaling pathway by inhibiting the activity of MDA-5 (also known as IFIH1). The cytoplasmic pattern recognition receptor MDA-5 detects dsRNA synthesized during active viral replication and triggers a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines.
Ontology:	GO: Biological Process [GO:0039554]    QuickGO    AmiGO