Term Name: | symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of RIG-I activity |
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Synonyms: | inhibition by virus of host DDX58 activity, inhibition by virus of host RIG-I, inhibition by virus of host RIG-I signaling, inhibition of host DDX58/RIG-I by virus, suppression by virus of host DDX58 signaling pathway, suppression by virus of host RIG-I activity, suppression by virus of host RIG-I signaling pathway, suppression by virus of host RIG-I signalling pathway, suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity, symbiont-mediated suppression of host RIG-I signaling pathway |
Definition: | A process in which a symbiont interferes with, inhibits or disrupts a cytoplasmic pattern recognition receptor signaling pathway by inhibiting the activity of RIG-1 (also known as DDX58). The cytoplasmic pattern recognition RIG-I recognizes viral RNA synthesized during active viral replication and signals to protect the host against viral infection, for example by inducing the expression of antiviral cytokines. |
Ontology: | GO: Biological Process [GO:0039540] QuickGO AmiGO |