Term Name: | granulocyte-macrophage colony-stimulating factor signaling pathway |
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Synonyms: | CSF2 signaling pathway, GM-CSF receptor signaling pathway, GM-CSF signaling pathway, granulocyte-macrophage colony-stimulating factor receptor signaling pathway, granulocyte-macrophage colony-stimulating factor signalling pathway |
Definition: | The series of molecular signals initiated by the binding of the cytokine granulocyte macrophage colony-stimulating factor (GM-CSF) to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. GM-CSF binds to a heterodimer receptor (CSF2R) consisting of an alpha ligand-binding subunit, and a common beta subunit that is shared with other cytokine receptors. |
Ontology: | GO: Biological Process [GO:0038157] QuickGO AmiGO |