Term Name: ERBB2-ERBB3 signaling pathway
Synonyms: ERBB2-ERBB3 signalling pathway, HER2-HER3 signaling pathway
Definition: The series of molecular signals initiated by binding of a ligand to a ERBB3 receptor on the surface of a cell, followed by transmission of the signal by a heterodimeric complex of ERBB2 and ERBB3. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB3. ERBB3 also has impaired kinase activity and relies on ERBB2 for activation and signal transmission.
Ontology: GO: Biological Process [GO:0038133]    QuickGO    AmiGO

Relationships
is a type of: ERBB2 signaling pathway ERBB3 signaling pathway