Term Name: | calcitriol biosynthetic process from calciol |
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Synonyms: | 1alpha,25(OH)2D3 biosynthesis, 1alpha,25-dihydroxycholecalciferol biosynthesis, 1alpha,25-dihydroxyvitamin D3 biosynthesis, calcitriol biosynthesis from calciol, vitamin D3 activation |
Definition: | Conversion of vitamin D3 from its largely inactive form (calciol, also called cholecalciferol) into a hormonally active form (calcitriol). Conversion requires 25-hydroxylation of calciol in the liver to form calcidiol, and subsequent 1,alpha-hydroxylation of calcidiol in the kidney to form calcitriol. |
Ontology: | GO: Biological Process [GO:0036378] QuickGO AmiGO |