Term Name:	tyrosyl-RNA phosphodiesterase activity
Synonyms:	unlinkase activity, uridylylpolynucleotide-(5' P->O)- tyrosine phosphodiesterase activity, VPg unlinkase activity, Y-pUpN PDE activity
Definition:	Catalysis of the hydrolysis of a 5' tyrosyl-RNA phosphodiester bond between a protein and RNA. In picornaviruses, this covalent bond connects VPg, a viral-encoded protein essential for RNA replication, to the 5' end of all nascent picornavirus genomes; it is cleaved from viral RNA prior to its engaging in protein synthesis.
Ontology:	GO: Molecular Function [GO:0036317]    QuickGO    AmiGO