Term Name: | senescence-associated heterochromatin focus |
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Synonyms: | SAHF, senescence-associated heterochromatin foci |
Definition: | A transcriptionally-silent heterochromatin structure present in senescent cells. Contains the condensed chromatin of one chromosome and is enriched for histone modifications. Thought to repress expression of proliferation-promoting genes. |
Ontology: | GO: Cellular Component [GO:0035985] QuickGO AmiGO |