Term Name: | site of double-strand break |
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Synonyms: | DNA damage foci, DNA damage focus, ionizing radiation-induced foci, IRIF, site of DSB |
Definition: | A region of a chromosome at which a DNA double-strand break has occurred. DNA damage signaling and repair proteins accumulate at the lesion to respond to the damage and repair the DNA to form a continuous DNA helix. |
Ontology: | GO: Cellular Component [GO:0035861] QuickGO AmiGO |