Term Name: | MH2 domain binding |
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Synonyms: | MAD homology 2 domain binding |
Definition: | Binding to a MH2 (MAD homology 2) protein domain. The MH2 domain is found at the carboxy-terminus of MAD related proteins such as Smads. The MH2 domain mediates interaction with a wide variety of proteins and provides specificity and selectivity to Smad function and also is critical for mediating interactions in Smad oligomers. |
Ontology: | GO: Molecular Function [GO:0035500] QuickGO AmiGO |