Term Name: | NuA4 histone acetyltransferase complex |
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Synonyms: | TIP60 histone acetylase complex, TIP60 histone acetyltransferase complex |
Definition: | A complex having histone acetylase activity on chromatin, as well as ATPase, DNA helicase and structural DNA binding activities. The complex is thought to be involved in double-strand DNA break repair. Subunits of the human complex include HTATIP/TIP60, TRRAP, RUVBL1, BUVBL2, beta-actin and BAF53/ACTL6A. In yeast, the complex has 13 subunits, including the catalytic subunit Esa1 (homologous to human Tip60). |
Ontology: | GO: Cellular Component [GO:0035267] QuickGO AmiGO |