Term Name: ESC/E(Z) complex
Synonyms: Extra Sex Combs/Enhancer of Zeste complex, polycomb repressive complex 2, PRC2 complex
Definition: A multimeric protein complex that can methylate lysine-27 and lysine-9 residues of histone H3. In Drosophila the core subunits of the complex include ESC, E(Z), CAF1 (NURF-55) and SU(Z)12. In mammals the core subunits of the complex include EED, EZH2, SUZ12 and RBBP4.
Ontology: GO: Cellular Component [GO:0035098]    QuickGO    AmiGO

Relationships
is a type of: histone methyltransferase complex PcG protein complex