Term Name: | conversion of discoidal high-density lipoprotein particle to spherical high-density lipoprotein particle |
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Synonyms: | conversion of discoidal HDL to spherical HDL, discoidal HDL remodeling, discoidal high-density lipoprotein remodeling |
Definition: | The process in which a discoidal high-density lipoprotein (HDL) particle acquires additional lipid or protein molecules, and cholesterol in the particle is converted to tightly bound cholesterol esters by the action of phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT), resulting in the formation of a spherical HDL particle. |
Ontology: | GO: Biological Process [GO:0034376] QuickGO AmiGO |