Term Name: | taurochenodeoxycholate 6alpha-hydroxylase activity |
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Synonyms: | CYP3A4, CYP4A21, taurochenodeoxycholate 6alpha-monooxygenase activity, taurochenodeoxycholate,NADPH:oxygen oxidoreductase (6alpha-hydroxylating) activity |
Definition: | Catalysis of the reaction: taurochenodeoxycholate + O2 + reduced [NADPH--hemoprotein reductase] + = taurohyocholate H+ + H2O + oxidized [NADPH--hemoprotein reductase]. Acts on taurochenodeoxycholate, taurodeoxycholate and less readily on lithocholate and chenodeoxycholate. |
Ontology: | GO: Molecular Function [GO:0033780] QuickGO AmiGO |