Term Name:	eukaryotic 48S preinitiation complex
Synonyms:	eukaryotic 48S initiation complex, eukaryotic 48S pre-initiation complex
Definition:	The protein-ribosome-tRNA complex that has just recognized the start codon of a capped mRNA. It is composed of the small ribosomal subunit, eukaryote initiation factors (eIF) eIF3 complex, eIF1, eIF1A, eIF2-GDP, eIF4 complex and initiatior-methionine-tRNA. Recognition of the start codon triggers downstream steps in the pathway, including eIF1 dissociation; Pi release from eIF2; and conversion to the closed, scanning-arrested conformation of the PIC.
Ontology:	GO: Cellular Component [GO:0033290]    QuickGO    AmiGO