Term Name: | leptin-mediated signaling pathway |
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Synonyms: | adipocytokine signaling pathway, leptin-mediated signalling pathway |
Definition: | The series of molecular signals initiated by leptin binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body. |
Ontology: | GO: Biological Process [GO:0033210] QuickGO AmiGO |