Term Name: | plasminogen activation |
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Synonyms: | cleavage of plasminogen to plasmin |
Definition: | The process in which inactive plasminogen is processed to active plasmin. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide. |
Ontology: | GO: Biological Process [GO:0031639] QuickGO AmiGO |