Term Name:	death-inducing signaling complex
Synonyms:	death receptor-induced signaling complex, death receptor-induced signalling complex, death-inducing signalling complex, DISC, DISC protein complex
Definition:	A protein complex formed by the association of signaling proteins with a death receptor upon ligand binding. The complex includes procaspases and death domain-containing proteins in addition to the ligand-bound receptor, and may control the activation of caspases 8 and 10.
Ontology:	GO: Cellular Component [GO:0031264]    QuickGO    AmiGO