Term Name: | pyrrolysine incorporation |
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Synonyms: | lysine methylamine methyltransferase cofactor adduct incorporation, monomethylamine methyltransferase cofactor lysine adduct incorporation |
Definition: | The incorporation of pyrrolysine, also known as lysine methylamine methyltransferase cofactor adduct, into a peptide; uses a special tRNA that recognizes the UAG codon as a modified lysine, rather than as a termination codon. Pyrrolysine may be synthesized as a free amino acid or synthesized from a lysine charged tRNA before its incorporation; it is not a posttranslational modification of peptidyl-lysine; this modification is found in several Methanosarcina methylamine methyltransferases. |
Ontology: | GO: Biological Process [GO:0030631] QuickGO AmiGO |