Term Name: | AP-1 adaptor complex |
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Synonyms: | AP-1 related adapter complex, HA1, HA1 clathrin adaptor |
Definition: | A heterotetrameric AP-type membrane coat adaptor complex that consists of beta1, gamma, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle; vesicles with AP-1-containing coats are normally found primarily in the trans-Golgi network. In at least humans, the AP-1 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (gamma1 and gamma2, mu1A and mu1B, and sigma1A, sigma1B and sigma1C). |
Ontology: | GO: Cellular Component [GO:0030121] QuickGO AmiGO |