Term Name: | dystrophin-associated glycoprotein complex |
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Synonyms: | DGC, dystrophin glycoprotein complex |
Definition: | A multiprotein complex that forms a strong mechanical link between the cytoskeleton and extracellular matrix; typical of, but not confined to, muscle cells. The complex is composed of transmembrane, cytoplasmic, and extracellular proteins, including dystrophin, sarcoglycans, dystroglycan, dystrobrevins, syntrophins, sarcospan, caveolin-3, and NO synthase. |
Ontology: | GO: Cellular Component [GO:0016010] QuickGO AmiGO |