Term Name: myotube differentiation
Synonyms:
Definition: The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
Ontology: GO: Biological Process [GO:0014902]    QuickGO    AmiGO

Relationships
has parts: myoblast fusion myotube cell development
is a type of: striated muscle cell differentiation
has subtype: myotube differentiation involved in skeletal muscle regeneration skeletal muscle fiber differentiation
negatively regulated by: negative regulation of myotube differentiation
positively regulated by: positive regulation of myotube differentiation
regulated by: regulation of myotube differentiation