Term Name: | protein kinase A signaling |
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Synonyms: | PKA signaling cascade, protein kinase A signal transduction, protein kinase A signaling cascade, protein kinase A signalling cascade |
Definition: | An intracellular signaling cassette that starts with the activation of protein kinase A (PKA), and ends with the regulation of a downstream cellular process, e.g. transcription. The PKA catalytic subunit (PKA-C) is normally present in a complex with its regulatory subunit, PKA-R. The inhibitory action of PKA-R is released upon cAMP binding, which results in the activation of PKA-C. |
Ontology: | GO: Biological Process [GO:0010737] QuickGO AmiGO |