Term Name: | JUN kinase kinase activity |
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Synonyms: | JNKK |
Definition: | Catalysis of the phosphorylation of tyrosine and threonine residues in a c-Jun NH2-terminal kinase (JNK), a member of a subgroup of mitogen-activated protein kinases (MAPKs), which signal in response to cytokines and exposure to environmental stress. JUN kinase kinase (JNKK) is a dual-specificity protein kinase kinase and requires activation by a serine/threonine kinase JUN kinase kinase kinase. |
Ontology: | GO: Molecular Function [GO:0008545] QuickGO AmiGO |