Term Name:	oxidized purine nucleobase lesion DNA N-glycosylase activity
Synonyms:	2,6-diamino-4-hydroxy-5(N-methyl)formamidopyrimidine-DNA glycosylase activity, 2,6-diamino-4-hydroxy-5N-formamidopyrimidine-DNA glycosylase activity, 8-oxoguanine DNA glycosylase activity, bifunctional DNA glycosylase activity, deoxyribonucleate glycosidase activity, DNA glycohydrolase [2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimide releasing], DNA glycosylase/AP-lyase activity, DNA glycosylase/beta-lyase activity, DNA-formamidopyrimidine glycosylase activity, Fapy-DNA glycosylase activity, formamidopyrimidine-DNA glycosylase activity, Fpg protein, oxidized purine base lesion DNA N-glycosylase activity, purine-specific oxidized base lesion DNA N-glycosylase activity
Definition:	Catalysis of the removal of oxidized purine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar. The reaction involves the formation of a covalent enzyme-substrate intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apurinic (AP) site.
Ontology:	GO: Molecular Function [GO:0008534]    QuickGO    AmiGO