Term Name: | folate:monoatomic anion antiporter activity |
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Synonyms: | folate:anion antiporter activity, reduced folate carrier activity, reduced folate transmembrane transporter activity, reduced folate transporter |
Definition: | Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Folate derivative (out) + anion (in) = folate derivative (in) + anion (out). The Reduced Folate Carrier (RCF(SLC19A1) acts by an antiport mechanism. RCF carries several folate derivatives: MTX, PMX, ratitrexed, pralatrexate, 5-methyl THF, and 5-formyl THF. |
Ontology: | GO: Molecular Function [GO:0008518] QuickGO AmiGO |